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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO1
All Species:
9.09
Human Site:
T318
Identified Species:
14.29
UniProt:
P21399
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21399
NP_002188.1
889
98399
T318
P
V
D
E
V
S
I
T
Y
L
V
Q
T
G
R
Chimpanzee
Pan troglodytes
XP_001155934
889
98362
T318
P
V
D
E
V
S
I
T
Y
L
V
Q
T
G
R
Rhesus Macaque
Macaca mulatta
XP_001103675
889
98487
T318
P
V
D
E
V
S
I
T
Y
L
V
Q
T
G
R
Dog
Lupus familis
XP_538698
889
98299
K318
P
V
D
E
V
S
I
K
Y
L
L
Q
T
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P28271
889
98160
A318
P
V
D
E
V
S
I
A
Y
L
L
Q
T
G
R
Rat
Rattus norvegicus
Q63270
889
98109
A318
P
V
D
D
V
S
I
A
Y
L
V
Q
T
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509375
889
98624
K318
P
V
D
D
I
S
V
K
Y
L
I
Q
T
G
R
Chicken
Gallus gallus
Q90875
889
98055
G318
P
V
D
D
I
S
I
G
Y
L
V
Q
T
G
R
Frog
Xenopus laevis
Q6NTP2
955
104418
Q387
P
V
D
S
V
T
L
Q
H
L
K
Q
T
G
V
Zebra Danio
Brachydanio rerio
NP_001030155
890
98920
Q318
P
V
D
Q
I
S
I
Q
Y
L
K
Q
T
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
G327
P
I
D
E
N
T
L
G
Y
M
K
Q
T
N
R
Honey Bee
Apis mellifera
XP_392993
890
98796
V320
P
I
D
Q
Q
S
L
V
Y
L
R
Q
T
G
R
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
D317
P
V
D
S
R
T
I
D
Y
L
T
Q
T
G
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SIB9
990
108183
Q414
P
V
D
H
V
T
L
Q
Y
L
K
L
T
G
R
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
G232
I
L
G
V
K
L
T
G
K
M
N
G
W
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
93.2
N.A.
93.4
92.9
N.A.
90.4
87.5
55.7
82.2
N.A.
67.9
69.4
62.9
N.A.
Protein Similarity:
100
100
99.5
96.9
N.A.
97.7
97.7
N.A.
95.1
93.8
72.2
92
N.A.
82.1
82.5
77.1
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
66.6
80
53.3
73.3
N.A.
46.6
60
66.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
73.3
86.6
N.A.
73.3
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.6
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
94
20
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
20
0
0
0
7
0
87
0
% G
% His:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
14
0
0
20
0
60
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
14
7
0
27
0
0
0
0
% K
% Leu:
0
7
0
0
0
7
27
0
0
87
14
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
94
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
14
7
0
0
20
0
0
0
87
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
87
% R
% Ser:
0
0
0
14
0
67
0
0
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
27
7
20
0
0
7
0
94
7
0
% T
% Val:
0
80
0
7
54
0
7
7
0
0
34
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
87
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _